ORIGINAL RESEARCH
published: 24 January 2022
doi: 10.3389/fpsyt.2021.820598
Frontiers in Psychiatry | www.frontiersin.org 1 January 2022 | Volume 12 | Article 820598
Edited by:
Khaled Saad,
Assiut University Hospital, Egypt
Reviewed by:
Islam Aud,
Al-Azhar University, Egypt
Bahaa Hawary,
Faculty of Medicine, Aswan
University, Egypt
*Correspondence:
Xin Zhang
zhangxin@tmu.edu.cn
Specialty section:
This article was submitted to
Child and Adolescent Psychiatry,
a section of the journal
Frontiers in Psychiatry
Received:23 November 2021
Accepted:15 December 2021
Published:24 January 2022
Citation:
Gao L, Wang C, Song X-r, Tian L,
Qu Z-y, Han Y and Zhang X (2022)
The Sensory Abnormality Mediated
Partially the Efficacy of Repetitive
Transcranial Magnetic Stimulation on
Treating Comorbid Sleep Disorder in
Autism Spectrum Disorder Children.
Front. Psychiatry 12:820598.
doi: 10.3389/fpsyt.2021.820598
The Sensory Abnormality Mediated
Partially the Efficacy of Repetitive
Transcranial Magnetic Stimulation on
Treating Comorbid Sleep Disorder in
Autism Spectrum Disorder Children
Lei Gao
1
, Chen Wang
1
, Xiao-rong Song
1
, Li Tian
2
, Zhi-yi Qu
1
, Yu Han
1
and Xin Zhang
1
*
1
Department of Maternal, Child and Adolescent Health, School of Public Health, Tianjin Medical University, Tianjin, China,
2
Department of Cerebral Functional Therapy, Tianjin AndingHospital (Tianjin Mental Health Center), Tianjin, China
Sleep disorder emerges as a common comorbidity in children with autism spectrum
disorder (ASD), and the interaction between the core symptoms of ASD and its sleep
disorder remains unclear. Repetitive transcranial magnetic stimulation (rTMS) was used
on the bilateral dorsolateral prefrontal cortex (DLPFC) toinvestigate the efficacy of rTMS
on the core symptoms of ASD and comorbid sleep problems as well as the mediation
role of the ASD symptoms between rTMS intervention and sleepimprovement. A total
of 41 Chinese children with ASD and who met the criteria in thefifth edition of th
外2022 Lei Gao CCY-I【5.435 Frontiers in psychiatry】重复经颅磁刺激治疗自闭症谱系障碍患儿共病性睡眠障碍的部分感觉异常作用CCY-I